
The Stressed Brain vs The Degenerating Brain
What Stress, Overload, and Hormones Really Do to Your Brain. Because putting your keys in the fridge isn't Alzhemiers (usually)...
If you’ve ever stood in the kitchen and forgotten why you’re there…
Lost words mid-sentence…
Put your keys in the fridge…
Read the same paragraph three times and still not retained it…
And then quietly thought: “Something is seriously wrong with me.This is early dementia.I am getting Alzheimer’s?”
You are not alone.
And in the vast majority of cases — this is not neurodgeneration. It’s a brain responding to stress, inflammation, hormonal shifts, poor sleep, and sustained overload.
Let’s talk about what is actually happening - without panic or judgement.
Stress Can Make You Feel Like You’re Losing Your Mind
Chronic stress floods the brain with cortisol — your main survival hormone.
In small, short bursts, cortisol is helpful. Over time, it becomes disruptive — not because the brain is broken, but because it’s prioritising survival over performance.
High cortisol directly affects three critical brain regions - The Hippocampus, the Pre-Frontal Cortex and the Amygdala.
The Hippocampus is the memory centre.This is your short-term memory and learning hub.
Research shows that prolonged cortisol exposure reduces neuron growth, shrinks hippocampal volume which then impairs memory formation.
This is why stress causes:
forgetting names
losing words
poor recall
difficulty learning new things
The Prefrontal Cortex is for thinking & focus
This controls:
organisation
reasoning
impulse control
emotional regulation
Stress suppresses this area and can result in:
you feel scattered
make silly mistakes
forget appointments
lose focus
struggle to plan or prioritise
The Amygdala is the fear and threat centre (so everything feels urgent). Stress strengthens this region which means:
more anxiety
more catastrophising
more emotional reactivity
more panic about your symptoms
So the brain both creates the fog… and then scares you about it.
Why Brain Fog From Stress Feels Like Dementia
The symptoms overlap so closely with cognitive decline:
short-term memory loss
word-finding difficulty
concentration problems
confusion under pressure
mental fatigue
slower processing
The key difference?
Stress makes your brain underperform.
Dementia destroys brain tissue.
In stress, information is harder to access..
In Alzheimer’s, the brain loses the ability to store new information permanently.
Sleep Deprivation Alone Can Mimic Cognitive Decline
Chronic poor sleep affects the brain profoundly by:
reducing memory consolidation
impairing attention
disrupting emotional regulation
increasing amyloid build-up (the protein linked to Alzheimer’s)
Just one week of insufficient sleep can:
reduce reaction time
impair working memory
lower attention span
increase emotional volatility
Now stack that on top of:
stress
hormones
gut inflammation
nutrient depletion
nervous system overload
And yes — you absolutely feel like your brain is failing.
Female Hormonal Changes can also Dramatically Affect the Brain
Oestrogen is neuro-protective. It supports:
memory
verbal processing
mood stability
focus
dopamine and serotonin balance
During perimenopause and menopause oestrogen fluctuates wildly, cortisol becomes more dominant, sleep worsens, anxiety increases and word recall declines.
This is why many women say: “I used to be sharp. Now I feel thick and slow.”
It is not intelligence loss.
It’s a change in neurochemistry.
Chronic Stress Alters Neurotransmitters
Long-term stress alters key brain messengers::
Serotonin - low mood, rumination, poor sleep
Dopamine - low motivation, loss of pleasure, brain fatigue
GABA - reduced calm, more anxiety
Acetylcholine - poor memory and learning
Acetylcholine reduction is particularly important — this is the SAME neurotransmitter affected in Alzheimer’s pathology, which is why the symptoms feel so similar.
But again — the mechanism is suppression, not destruction:
stress suppresses
neurodegeneration destroys
Inflammation Makes the Brain Foggy
Gut inflammation, blood sugar instability, immune activation and chronic infections all increase neuroinflammation.
Inflamed brains:
process more slowly
fatigue faster
struggle with clarity
lose verbal fluency
This is why brain fog often accompanies:
sugar crashes
adrenal fatigue
gut issues
chronic infections
autoimmune flares
All create major brain fog.
And then anxiety comes in and makes You Feel Worse Than You Are
Anxiety magnifies awareness and amplifies the experience.
You may notice you start:
scanning for symptoms
monitoring every lapse
catastrophising every mistake
assuming the worst
Which drives more cortisol…Which further reduces memory access.
It becomes a self-reinforcing cognitive stress loop - not a failing mind
The Most Important thing to know and the one to focus on…
Stress-Based Brain Fog Is Reversible
Unlike true neurodegenerative disease, stress-related cognitive decline responds exceptionally well to:
nervous system regulation
sleep restoration
blood sugar stability
hormone support
nutritional therapy
trauma resolution
emotional processing
gut repair
cognitive retraining
When load reduces:
hippocampal cells regenerate
memory improves
word retrieval returns
clarity sharpens
emotional control stabilises
A Reassuring Reality Check
If you:
function well in calm moments
remember things when relaxed
improve with good sleep
think clearly on holiday
struggle mainly when overwhelmed
That strongly points toward stress-driven cognitive suppression — not dementia.
In other words, you are not losing your mind and you are not “getting Alzheimer’s overnight.”
Brain fog is not a diagnosis. It is a message.
And it is one of the most treatable brain states there is.


